Prolonged executive overload downregulates prefrontal glucocorticoid receptors, breaking stress inhibition; recovery requires strict thread gating to restore receptor sensitivity.
Intense enterprise insolvency induces cellular glucocorticoid receptor resistance through chaperone shifts and altered phosphorylation, blunting tissue sensitivity.
Extended high-stakes load downregulates central glucocorticoid receptor sensitivity, flattening cortisol rhythms and reducing executive processing headroom.
The terms are written where they belong. Each field holds three desks, and every entry a desk writes raises the terms it uses, each term given a meaning, a mechanism and the places it appears. The record on these pages stays first person and hand made; the fields grow the nomenclature.
